An essential separations technique for your laboratory
UltraPerformance Convergence Chromatography™ (UPC2®) is a broad-based, complementary analytical platform that is taking its place alongside of LC and GC as one of the three essential separation technologies for modern laboratory analysis. There are three main forms of chromatography: GC, LC, and now convergence chromatography (CC). While all three use a stationary phase to interact with compounds of interest and a mobile phase to move compounds through the stationary phase and achieve separation, the techniques differ mainly by the mobile phases used.
Orthogonality you can rely on
A major concern of scientists in regulated industries is that impurity, degradation peaks, or structurally similar compounds may be overlooked. Orthogonal methods that provide different elution orders of peaks are needed to ensure full characterization and that nothing is overlooked. Having a second technology platform that can routinely provide reliable orthogonal data is proving to be a strong driver for UPC2 adoption.
When reversed-phase chromatography was introduced, scientists moved quickly away from normal-phase chromatography. Among the advantages that reversed-phase chromatography offers are ruggedness and reliability, as well as the power of gradient elution for rapid method development, these capabilities significantly improve workflow and were not possible with normal-phase LC.web site