nanoACQUITY UPLC System with HDX Technology


The nanoACQUITY UPLC® System with HDX Technology leverages UPLC® separations and high-resolution MS to answer important questions about changes in protein conformation including:

  • Drug binding to a protein
  • Biopharmaceutical product development
  • Protein-protein interactions
  • Structural biology

The unprecedented system-level design integrates all the steps necessary to accurately, reproducibly, and most of all, easily, perform protein conformation studies.  The system and its DynamX™ HDX Data Analysis Software removes the barriers to adopting high resolution LC and MS for routine studies of protein conformational changes, making hydrogen deuterium exchange with MS (HDX, HDX MS, HXMS, or H/D exchange) a core competency for your laboratory.

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