MALDI SYNAPT G2-Si High Definition Mass Spectrometry

Redefining Resolution - Resolution in 3 Dimensions

MALDI SYNAPT G2-Si is a uniquely powerful and versatile MS platform. It's the only way to combine multiple dimensions of separation for analysis of complex samples, from imaging to biological research to chemical materials characterization.

  • High Performance, Accurate Mass MALDI MS/MS
  • Superior post-ionization separation with T-Wave IMS
  • High Definition Imaging (HDI) MALDI workflows
  • Versatile Experimental Options
  • Ultimate UPLC/MS/MS Performance

High Performance, Accurate Mass MALDI MS/MS

The MALDI SYNAPT G2-Si MS System enables you to produce optimal results for imaging, chemical materials characterization, proteomics and pharmaceutical applications. The MALDI SYNAPT G2-Si is powered by a solid state laser with a repetition rate of 2.5KHz to maximize the speed of your analysis. The laser spot size can be selected for optimising sensitivity and speed of analysis, or for maximizing spatial resolution in Imaging studies.

Due to the orthogonal geometry of the Tof analyzer, the source is decoupled from the mass analysis. So, unlike axial MALDI-Tof or Tof/Tof instruments, this ensures that high resolution and accurate mass are achieved in both MS and MS/MS modes across a wide mass range. In addition, SYNAPT is well suited to nonconductive samples such as paraffin embedded tissue sections on glass slides.

High Definition Imaging (HDI) MALDI workflows

MALDI SYNAPT G2-Si HDMS combines T-Wave IMS and QuanTof technology within a streamlined imaging workflow to deliver unparalleled selectivity, clarity and confidence.

The HDI MALDI solution provides a unique range of powerful multiplex targeted (IMS/MS/MS) and untargeted (IMS/MSE) workflows from image-centric method set-up to data processing and image generation. Integrated correlation (based on spatial location drift-time related fragment ions) and statistical tools (e.g. PCA, OPLS-DA, S-plots, hierarchical clustering) also combine to deliver more intelligent and confident imaging analysis.

With the ability to access full UPLC/MS/MS capability on SYNAPT, you also have the power of high performance quantitative and discovery analysis from bio-fluids or laser-dissected tissue sections on the same platform.

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