Drug Formulation and Development

Drug formulation and development requires highly accurate characterization of biomolecules to predict their behavior in the body and the efficacy of their treatment. Active pharmaceutical ingredients (APIs) and their inactive carriers, or excipients, must be tested for their compatibility and chemical stability. Pharmaceutical developments are also optimized for bioavailability in the body. Rheology helps developers measure the flow behavior of liquids during drug production as well as the viscosity and yield stress of formulations to maintain drug suspension. In topical ointments, emulsion stability is optimized to prevent phase separation.

Sorption Analysis (SA) is used to assess hygroscopicity, amorphous – crystalline phase changes, and hydrate formation.