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TA Instruments · Pharmaceuticals

Research and Discovery

Pharmaceutical research and discovery is a challenging yet rewarding process that results in the treatment of a disease or clinical condition through new…

Research and Discovery

Pharmaceutical research and discovery is a challenging yet rewarding process that results in the treatment of a disease or clinical condition through new medicine. First, researchers must find a biological target that plays a role in the disease and can be singled out for treatment. During lead discovery, researchers find small molecules or biological therapeutics that they can test as a development candidate. Lead optimization and pre-formulation involve testing and improving crucial characteristics in the lead so it can be properly absorbed for the intended treatment.

Calorimetry is used to characterize minute interactions between macromolecules, while gas analysis and sorption analysis measures the thermal stability and moisture content of pharmaceutical compounds.