CG-MALS

Label-free, immobilization-free characterization of protein-protein and other macromolecular interactions with composition-gradient multi-angle light scattering.

The Calypso II, in conjunction with a DAWN™ or miniDAWN™ MALS detector, measures binding affinities and absolute, molecular stoichiometries of complex biomolecular interactions.

Weight-Average Molar Mass

In addition to equilibrium association constants Kd and absolute stoichiometry of reversible self- and hetero-associations, it can also help determine reaction or aggregation rates, non-specific interaction parameters (virial coefficients) and even automate measurements of weight-average molar mass and dn/dc for polymers.

CALYPSO™ Software

Included with each Calypso is a copy of CALYPSO software, the most versatile software package available for analysis of biomolecular interactions in solution by light scattering.