Vaccines
To ensure safe and efficacious vaccines, it is essential to implement robust and reliable characterization tools across discovery, development, production and quality control.

Wyatt’s suite of solutions analyzes critical vaccine attributes, including:
Molar mass and size
Viral physical titer and nucleic acid content
Aggregation
Thermal and colloidal stability
Many of these assays can be streamlined and automated for high throughput.
Our technologies are also helpful in vaccine research and process development, for studying the binding affinity and stoichiometry of antibody-antigen complexes, the oligomeric state of surface glycoproteins, or optimizing formulation conditions.
Continue reading to learn how Wyatt products are applied to characterization of specific vaccine classes.
Agregasyon

mRNA/DNA
mRNA biophysical attributes
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Viruses (inactivated or live-attenuated)
These complex vaccine products combine multiple serotypes, often with adjuvants. Asymmetric-flow field-flow fractionation (AF4) separates such complex samples…
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Virus-like particles (VLPs)
Recombinant virus-like particles, which are designed to elicit an immune response in the same way that a traditional live-attenuated vaccine does, are…
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Polysaccharide and glycoconjugate vaccines
Polysaccharide and protein glycoconjugate vaccines combine adjuvants with high-molecular-weight polysaccharide antigens, typically including several serotypes.…
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