Waters · Chromatography Consumables & Supplies
OligoWorks SPE Kits & Components
High recoveries across a diverse range oligotherapeutic modalities
OligoWorks SPE kits are designed to simplify and accelerate the extraction of oligonucleotide-based drugs and metabolites from biofluids (plasma, urine, tissue homogenates), and to deliver maximum LC-MS sensitivity and repeatability across a diverse range of oligonucleotide therapeutics, including lipid-conjugated species.
OligoWorks WAX sorbent is quality control tested and batch-selected for maximum oligonucleotide recovery, and a robust detergent-free protocol reduces method development and produces a clean concentrated eluate that is ready for direct LC-MS analysis - avoiding the need for evaporation and reconstitution.