FFF-MALS: Extended aggregate characterization

For the characterization of large AAV aggregates or other large species, field-flow fractionation in combination with MALS (FFF-MALS) is the method of choice. The Eclipse™ FFF system separates particles from 1 – 1000 nm in an open channel with no stationary phase and is invaluable for analyzing particles that are too large for separation by SEC or may be removed or dissociated by column shear.